What is a common effect of opioid overdose?

Respiratory depression is a primary and dangerous effect of opioid overdose. Opioids work by binding to specific receptors in the brain and spinal cord, which can lead to a decrease in the signals that stimulate breathing. This suppression of the respiratory system can result in significantly reduced respiratory rate and depth, which may lead to insufficient oxygenation of the body and can be life-threatening. Recognizing respiratory depression is crucial for emergency response to opioid overdose, as it may require interventions such as the administration of naloxone (Narcan) to reverse the effects of the overdose and restore normal breathing. This understanding is important for identifying interventions and seeking immediate medical help in an overdose situation.